A talk at the GME (Genomes, Medicine and Environment) Conference in 2007 by Jonathan A. Eisen. The talk is about the creation of "A Genomic Encyclopedia of Bacteria and Archaea - GEBA"

A simple classification scheme that uses only the presence or absence of a protein domain architecture has been used to determine the phylogeny of 174 complete genomes. The method correctly divides the 174 taxa into Archaea, Bacteria, and Eukarya and satisfactorily sorts most of the major groups within these superkingdoms. The most challenging problem involved 119 Bacteria, many of which have reduced genomes. When a weighting factor was used that takes account of difference in genome size...